Treating Psychosocial Distress in Glaucoma
Completed · Not applicable
Conditions studied: Glaucoma, Primary Open Angle, Distress, Emotional, Anxiety, Depression
In brief
In this study, using three phases, the investigators will use an iterative development approach to refine a behavioral intervention for managing concomitant psychosocial distress in glaucoma. Phase 1: The investigators will begin by developing a baseline intervention using strategies from Acceptance and Commitment Therapy (ACT), and delivered using a mobile application. Phase 2: The investigators will refine the baseline intervention for glaucoma patients using qualitative interviews conducted with primary open-angle glaucoma (POAG) patients with psychosocial distress (N=20), and health professionals (N=5). Phase 3: Finally, the investigators will measure acceptability and feasibility of the refined intervention through a single-armed pilot study (N=25). The investigators hypothesize that the refined intervention will yield an acceptable and feasible intervention in a POAG patient population, setting the stage for a future efficacy study.
Key facts
- Study ID
- NCT06053307
- Run by
- Duke University
- People needed
- 28
- Starts
- 2025-04-01
- Expected to finish
- 2026-01-26
- Last updated by the study team
- 2026-03-18
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- diagnosed with mild, moderate, or severe chronic glaucoma (e.g., POAG),
- had a visual field within the past year at the main Duke Eye Center,
- been prescribed pressure lowering eye drop medication,
- at least mild distress (based on PHQ-4),
- 18 years old,
- able to understand, speak, and read English, and
- be able to provide informed consent.
You may not qualify if…
- diagnosed with borderline glaucoma or as a glaucoma suspect,
- had a glaucoma surgery in past month (e.g., trabeculectomy, glaucoma drainage device/tube),
- visual acuity of worse than 20/70 in the better seeing eye,
- diagnosed with a major medical conditions (e.g., cancer, or another visual disorder, like macular degeneration),
- diagnosed with a psychiatric conditions (e.g., schizophrenia, bipolar disorder), and
- reported or suspected cognitive impairment indicated by provider or chart review.
Where it is running
- Duke University Eye Center — Durham, North Carolina, United States
Full record on ClinicalTrials.gov
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