NIV for Hypercapnic Respiratory Failure: AVAPS vs S/T BIPAP
Recruiting now · Not applicable
Conditions studied: Hypercapnic Respiratory Failure
In brief
The goal of this study is to compare two different modes of noninvasive ventilation in hypercapnic respiratory failure. The investigators will compare AVAPS and BIPAP S/T and hypothesize that AVAPS will result in a decreased length of stay in the ICU or on telemetry. Currently, noninvasive ventilation is the standard of care for hypercapnic respiratory failure. However, the most effective mode for patients with hypercapnic respiratory failure is unclear.
Key facts
- Study ID
- NCT06047405
- Run by
- Northwell Health
- People needed
- 100
- Starts
- 2023-10-07
- Expected to finish
- 2026-09-01
- Last updated by the study team
- 2023-10-31
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Provision of signed and dated informed consent form directly by the patient; consent can also be obtained via a legal patient representative/health care proxy/surrogate
- Stated willingness to comply with all study procedures and availability for the duration of the study
- Male or female, aged 18 or older
- Diagnosed with hypercapnic respiratory failure on admission (ABG)
- Admitted to Lenox Hill Hospital medical intensive care unit or telemetry unit
- Requiring noninvasive ventilation as determined by the treating physician for the treatment of hypercarbic respiratory failure
You may not qualify if…
- Patients who require ventilation at predetermined tidal volumes
- Patients who require rapid and frequent IPAP adjustments to maintain a consistent tidal volume
- Age less than 18 years of age
- Currently intubated
- Chronic tracheostomy
- Pregnancy
- Hypotension
- Epistaxis (nosebleed)
- Untreated pertussis
- Acute sinusitis or Otitis media
- Patients at risk of aspirating gastric contents
- Patients with lack of spontaneous respiratory drive
- Patients with the inability to maintain a patent airway or adequately clear secretions
- Prisoners or other institutionalized individuals
Where it is running
- Lenox Hill Hospital — New York, New York, United States (enrolling)
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.