Anti-Inflammatory Effects of 0.045% Tazarotene/0.01% Halobetasol Lotion in Psoriasis
Completed · Phase 4
Conditions studied: Psoriasis Vulgaris
In brief
The objective of this research is to demonstrate superior anti-inflammatory effects, as demonstrated by a reduction in TNF-a and IL-17A, with tazarotene/halobetasol lotion in patients with mild to moderate plaque type psoriasis as compared to clobetasol propionate 0.05% cream.
Key facts
- Study ID
- NCT06042647
- Run by
- Dermatology Consulting Services, PLLC
- People needed
- 10
- Starts
- 2023-07-13
- Expected to finish
- 2023-11-13
- Last updated by the study team
- 2023-11-18
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Males or non-pregnant females 18+ years of age.
- Plaque type mild to moderate psoriasis suitable for topical treatment.
- The presence of 2 plaques suitable for tape stripping
- Subjects must be willing to allow a series of tape pieces to be pressed and removed from 2 target psoriasis plaques.
- Subjects must be in general good health as determined from a medical history.
- Subjects must read and sign the informed consent form after the nature of the study has been fully explained.
You may not qualify if…
- Subjects with known allergies or sensitivities to ingredients contained in the test products.
- Subjects with an allergy to latex or adhesives.
- Subjects with pustular or erythrodermic psoriasis.
- Subjects who are pregnant or nursing or planning to become pregnant during the course of the study.
- Subjects who are currently participating in any other clinical study (i.e., dermal patch, use tests, investigational drug or devices, etc.).
- Subjects viewed by the investigator as not being able to complete the study.
- Subjects using any type of lotion, medication, or other topical product to the psoriasis plaques.
Where it is running
- Dermatology Consulting Services, PLLC — High Point, North Carolina, United States
Full record on ClinicalTrials.gov
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