Firefighter Thermoregulatory Responses in Active Fire with Betaine Supplementation

Completed · Not applicable · Has a placebo group

Conditions studied: Body Temperature Changes, Body Water Dehydration, Inflammation

In brief

The goal of this clinical trial is to compare betaine supplementation to placebo in firefighters undergoing live burn training regarding thermoregulation and inflammation. The main questions it aims to answer are: * Does betaine supplementation mitigate rises in core temperature during firefighter live burn training? * Does betaine supplementation decrease inflammation from firefighter training? * Does betaine supplementation increase total body water stores? Participants will supplement with betaine for 1 month and complete: * Total Body Water measures * Body Composition measures * Live Burn training with Core Temperature Measurements * Provide Salivary samples

Key facts

Study ID

NCT06042270

Run by

Michael J. Ormsbee

People needed

17

Starts

2023-12-20

Expected to finish

2024-09-01

Last updated by the study team

2024-10-17

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Structural Firefighter

You may not qualify if…

• • Participants have a cardiometabolic disease for which they take prescribed medications
• Participants consume supplements known to impact hydration status or performance that they are not willing to stop taking for the study
• Participants are pregnant
• Female participants that have irregular menstrual cycles
• Participants are injured and would not be able to fulfill the live burn scenario
• Participants have sickle cell disease
• Participants have experienced heat stroke within the last 2 years

Where it is running

• Institute of Sports Science and Medicine — Tallahassee, Florida, United States

Full record on ClinicalTrials.gov

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