Using E-Nose Technology to Measure Response to Treatment in People With Malignant Pleural Mesothelioma

Recruiting now · Not applicable

Conditions studied: Malignant Pleural Mesothelioma

In brief

The researchers are doing this study to test the ability of a new technology called breathprinting, or electronic nose (E-Nose), to measure how people respond to standard treatment for malignant pleural mesothelioma (MPM). The researchers will study how E-Nose breathprints change over time as people receive standard treatment for MPM. They will also look at how changes in people's E-Nose breathprints compare to changes in their standard imaging scans and in biomarkers of MPM in their blood.

Key facts

Study ID

NCT06037941

Run by

Memorial Sloan Kettering Cancer Center

People needed

20

Starts

2023-09-08

Expected to finish

2026-09-01

Last updated by the study team

2025-09-22

Who can join

Age: 30 and older, up to 85. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Aged 30-85 years
• No history of thoracic cancer or extrathoracic cancer potentially involving pleural metastases (i.e., breast, gastric, colon, or pancreas cancer)
• Recent diagnosis of MPM
• Documented, signed, and dated informed consent, obtained before any procedures, for the proposed research study, and signed standard surgical consent for surgical resection

You may not qualify if…

• Aged <30 or >85 years at the first outpatient visit
• History of thoracic or extrathoracic cancer that puts the subject at risk for pleural or pulmonary metastases

Where it is running

• Memorial Sloan Kettering Basking Ridge (Consent Only) — Basking Ridge, New Jersey, United States (enrolling)
• Memorial Sloan Kettering Monmouth (Consent Only) — Middletown, New Jersey, United States (enrolling)
• Memorial Sloan Kettering Bergen (Consent Only ) — Montvale, New Jersey, United States (enrolling)
• Memorial Sloan Kettering Cancer Center @ Suffolk-Commack (Consent Only) — Commack, New York, United States (enrolling)
• Memorial Sloan Kettering Westchester (Consent Only) — Harrison, New York, United States (enrolling)
• Memorial Sloan Kettering Cancer Center (All Protocol Activities) — New York, New York, United States (enrolling)
• Memorial Sloan Kettering Nassau (Consent Only) — Uniondale, New York, United States (enrolling)

Full record on ClinicalTrials.gov

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