NMR Based Metabolomics Kinetics in ARDS Patients

Recruiting now

Conditions studied: ARDS

In brief

Acute respiratory distress syndrome (ARDS) is a life-threatening condition requiring respiratory support to maintain oxygenation. Very few biomarkers about ARDS have been identified but none of them has a sufficient specificity or sensitivity to characterize by itself the severity of lung condition. Investigators hypothesize that there is considerable change occurring in metabolic profiles in mild, moderate, and severe ARDS in comparison to healthy cohort, which can be detectable through serum analysis using NMR based metabolomics study. This research would help to understand metabolomics kinetics during the ARDS disease progression. Overall, NMR-based metabolomics study would provide an insight into the mediators involved in pathogenesis and progression of ARDS.

Key facts

Study ID

NCT06036056

Run by

Sanjay Gandhi Postgraduate Institute of Medical Sciences

People needed

120

Starts

2023-09-13

Expected to finish

2025-09-01

Last updated by the study team

2024-11-27

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Critically ill adult patients having mild ARDS with onset less than 72 hours

You may not qualify if…

• Age less than 18 years or more than 65 years
• Expected survival <72 hours
• Refusal from family member

Where it is running

• Centre of Biomedical Research — Lucknow, Uttar Pradesh, India (enrolling)

Full record on ClinicalTrials.gov

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