Inactivity Duration on Lipid Metabolism

Completed · Not applicable

Conditions studied: Metabolism

In brief

The purpose of the study is to investigate the effect of different periods of physical inactivity on postprandial lipid metabolism in the morning after exercise by measuring plasma triglyceride levels and fat oxidation (burning). The study is a crossover intervention with all healthy participants performing three trials varying in length of physical inactive (12 hours, 24 hours, and 36 hours). All trials include a physical activity control phase (\>10,000 steps/24hr), a physical inactive phase (\<1,000 - 1,500 steps/12hr), a moderate intensity cycling session, and a high-fat tolerance test.

Key facts

Study ID

NCT06033898

Run by

University of Texas at Austin

People needed

8

Starts

2023-10-01

Expected to finish

2024-05-12

Last updated by the study team

2025-03-03

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Healthy male or female between the age of 18-65 years old
• Untrained or recreationally active
• No metabolic disease, no lactose intolerance, not taking medicines altering lipid or carbohydrate metabolism
• No injury or disease affecting the cycling ability.

You may not qualify if…

• On medications that alter lipid or carbohydrate metabolism
• lactose intolerant
• General health problems: Heart problems or coronary artery disease, hypertension, lung or respiratory problems.
• Exercise problems: Chest pain, fainting, palpitations, told to give up sports because of health problems.

Where it is running

• The University of Texas at Austin — Austin, Texas, United States

Full record on ClinicalTrials.gov

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