Study of GS-0272 in Participants With Rheumatoid Arthritis
Stopped early · Phase 1 · Has a placebo group
Conditions studied: Rheumatoid Arthritis
In brief
The goals of this clinical study are to learn more about the study drug, GS-0272, and its safety and tolerability following multiple doses in participants with rheumatoid arthritis (RA). The primary objectives of this study are to assess the safety and tolerability of multiple ascending doses of GS-0272 and to characterize the pharmacokinetics of GS-0272 following multiple doses of GS-0272, in participants with RA.
Key facts
- Study ID
- NCT06031415
- Run by
- Gilead Sciences
- People needed
- 55
- Starts
- 2023-09-28
- Expected to finish
- 2026-05-11
- Last updated by the study team
- 2026-05-27
Who can join
Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.
Where it is running
- NIHR Wellcome Trust Clinical Research Facility, University Hospital Southampton NHS Foundation Trust — Southampton, United Kingdom
- Simbec Research Limited — Merthyr Tydfil, United Kingdom
- Arizona Arthritis & Rheumatology Associates P.C. — Glendale, California, United States
- Stanford School of Medicine, Division of Immunology & Rheumatology — Palo Alto, California, United States
- 1238 E. Arrow Hwy — Upland, California, United States
- Clinical Research of West Florida, Inc. — Clearwater, Florida, United States
- Jacksonville Center for Clinical Research — Jacksonville, Florida, United States
- Greater Chicago Specialty Physicians/ Clinical Investigation Specialists — Niles, Illinois, United States
- Greater Chicago Specialty Physicians/Clinical Investigation Specialists, Inc. — Schaumburg, Illinois, United States
- Summit Headlands LLC — Portland, Oregon, United States
- Altoona Center for Clinical Research — Duncansville, Pennsylvania, United States
- PA Regional Center for Arthritis and Osteoporosis Research — Wyomissing, Pennsylvania, United States
- Precision Comprehensive Clinical Research Solutions — Colleyville, Texas, United States
- Accurate Clinical Research, Inc. — Houston, Texas, United States
- Precision Comprehensive Clinical Research Solutions — Irving, Texas, United States
- 1600 Republic Parkway — Mesquite, Texas, United States
- ARENSIA Exploratory Medicine LLC — Tbilisi, Georgia
- IMSP Republican Clinical Hospital "Timofei Mosneaga", ARENSIA E.M. — Chisinau, Moldova
- Chungnam National University Hospital — Daejeon, South Korea
- Seoul National University Hospital — Seoul, South Korea
- Ajou University Hospital — Suwon, South Korea
- Cambridge Clinical Research Centre, Rheumatology Research Unit - E6, Addenbrookes Hospital — Cambridge, United Kingdom
- University Hospitals Coventry & Warwickshire NHS Trust — Coventry, United Kingdom
- Kings College Hospital — London, United Kingdom
Full record on ClinicalTrials.gov
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