Study of Tilpisertib Fosmecarbil in Participants With Moderately to Severely Active Ulcerative Colitis
Recruiting now · Phase 2 · Has a placebo group
Conditions studied: Ulcerative Colitis
In brief
The goal of this study is to learn if tilpisertib fosmecarbil (formerly known as GS-5290) is effective and safe in treating participants with moderate to severe ulcerative colitis. The study will compare participants in different treatment groups treated with tilpisertib fosmecarbil with participants treated with placebo. The primary objective of this study is to demonstrate the efficacy of tilpisertib fosmecarbil, compared to placebo control, in achieving Clinical Response at Week 12.
Key facts
- Study ID
- NCT06029972
- Run by
- Gilead Sciences
- People needed
- 176
- Starts
- 2023-12-05
- Expected to finish
- 2028-02-01
- Last updated by the study team
- 2026-02-11
Who can join
Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Digestive Health Specialists — Tupelo, Mississippi, United States (enrolling)
- NYU Langone Long Island Clinical Research Associates — Great Neck, New York, United States (enrolling)
- Mayo Clinic — Rochester, Minnesota, United States (enrolling)
- Gastroenterology Associates of North Mississippi — Oxford, Mississippi, United States (enrolling)
- St. Charles Clinical Research — St Louis, Missouri, United States (enrolling)
- Southern California Research Centers — Coronado, California, United States (enrolling)
- VVCRD Research — Garden Grove, California, United States (enrolling)
- Corewell Health — Grand Rapids, Michigan, United States (enrolling)
- GI Alliance — Sun City, Arizona, United States (enrolling)
- UC San Diego Health System — La Jolla, California, United States (enrolling)
- Gastro Care Institute — Lancaster, California, United States (enrolling)
- University of Florida — Gainesville, Florida, United States (enrolling)
- The Medici Medical Research — Hollywood, Florida, United States (enrolling)
- Om Research LLC — Lancaster, California, United States (enrolling)
- Clinical Research of Osceola — Kissimmee, Florida, United States (enrolling)
- Florida Research Institute — Largo, Florida, United States (enrolling)
- University of California, Davis — Sacramento, California, United States (enrolling)
- GastroSb Weight Loss Clinic — Chula Vista, California, United States (enrolling)
- University of California San Francisco — San Francisco, California, United States (enrolling)
- GI PROS Research — Naples, Florida, United States (enrolling)
- Clinical One Research — Orlando, Florida, United States (enrolling)
- Digestive and Liver Center of Florida, LLC — Orlando, Florida, United States (enrolling)
- Advanced Medical Research Center — Port Orange, Florida, United States (enrolling)
- Luna Research — Coral Gables, Florida, United States (enrolling)
- Gastroenterology & Hepatology Specialists Inc — Canton, Ohio, United States (enrolling)
Full record on ClinicalTrials.gov
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