MR Elastography of Cognitive Impairment

Enrolling by invitation

Conditions studied: Alzheimer Disease, Mild Cognitive Impairment, Healthy

In brief

The purpose of this research is to further investigate the potential of brain stiffness as a novel biomarker for Alzheimer's disease.

Key facts

Study ID

NCT06029114

Run by

Mayo Clinic

People needed

450

Starts

2023-10-11

Expected to finish

2027-11-01

Last updated by the study team

2026-01-13

Who can join

Age: 18 and older, up to 100. Sex: any. Healthy volunteers: accepted.

You may not qualify if…

• Alzheimer's disease or mild cognitive impairment due to a known genetic mutation
• Major depression
• History of primary or metastatic intracranial neoplasm, significant head trauma, intra-cerebral hemorrhage, hemispheric stroke
• Contradictions to MRI imaging including but not limited to cardiac pacemakers, intraocular or intracranial metal, or other MRI incompatible devices.
• Pregnant women. Women of child bearing potential will be given a urine pregnancy test prior the MRI scan. Results will be shared with the participant. If the pregnancy test is positive, the participant will not be included within the study

Where it is running

• Mayo Clinic Minnesota — Rochester, Minnesota, United States

Full record on ClinicalTrials.gov

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