Individualized Treatments in Adults With Relapsed/Refractory Cancers
Completed · Not applicable
Conditions studied: Refractory Cancer, Relapsed Cancer
In brief
A personalized cancer medicine approach would address therapy resistance, cancer metastasis, and limited options after standard of care is exhausted in advanced cancer participants. This approach may reduce the barriers to approved therapeutic assignment currently limited to a particular cancer type or patient demographic.
Key facts
- Study ID
- NCT06024603
- Run by
- Case Comprehensive Cancer Center
- People needed
- 36
- Starts
- 2023-11-20
- Expected to finish
- 2025-12-31
- Last updated by the study team
- 2026-07-06
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Participants aged 18 years or older at the time of enrollment on this study of any gender, race, or ethnicity.
- Patients with suspected or confirmed diagnosis of recurrent or refractory cancer with no curative treatment options.
- Participants who have undergone at least two lines of previous therapy.
- Participants who are scheduled for or have recently had biopsy or tumor excised (solid tumors) or bone marrow aspirate (blood cancers) or who have scheduled or recently had paracentesis or thoracentesis performed.
- Participants willing to have a blood draw or buccal swab done for the purposes of genetic testing.
- Participants willing to sign informed consent.
You may not qualify if…
- Participants who do not have malignant tissue available and accessible.
- Participants for whom the amount of excised malignant tissue is not sufficient for the ex vivo drug testing and/or genetic profiling.
- Participants with newly diagnosed tumors and tumors that have high (>90%) cure rate with safe standard therapy.
Where it is running
- Florida International University — Miami, Florida, United States
- Lerner College of Medicine, Cleveland Clinic Florida — Weston, Florida, United States
Full record on ClinicalTrials.gov
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