Sex Hormones, Postoperative Pain and Opioid Use

Recruiting now

Conditions studied: Postoperative Pain, Opioid Use

In brief

Aim 1- To identify relationships between sex hormone levels and postoperative pain and opioid use. Aim 2: To determine whether the effects of testosterone on postoperative pain and opioid use are mediated by immune factors

Key facts

Study ID

NCT06023225

Run by

Washington University School of Medicine

People needed

210

Starts

2023-09-01

Expected to finish

2029-07-01

Last updated by the study team

2026-07-13

Who can join

Age: 11 and older, up to 16. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Pediatric female patients between the ages 11-16 undergoing an orthopedic (trauma and non-trauma) surgical procedure involving a long bone or joint, or the spine, English speaking

You may not qualify if…

• Pregnancy; Diagnosis of chronic pain, Psychiatric, developmental or neurological disorders, Disorders that are associated with pubertal maturation (e.g., precocious puberty).

Where it is running

• Washington University School of Medicine — St Louis, Missouri, United States (enrolling)

Full record on ClinicalTrials.gov

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