Tranexamic Acid Use for Bleeding Prevention in the Surgical Treatment of Metastatic Spinal Tumor in Lung Cancer Patients

Recruiting now · Phase 1/Phase 2

Conditions studied: Metastasis Spinal Tumor

In brief

Massive blood loss occurs in metastatic spinal tumor resection and may cause severe complications. The objective of this study is to investigate whether the use of tranexamic acid will reduce perioperative and postoperative bleeding when compared to those without use of tranexamic acid.

Key facts

Study ID

NCT06023212

Run by

Second Affiliated Hospital, Zhejiang University, School of Medicine

People needed

150

Starts

2023-12-01

Expected to finish

2026-08-01

Last updated by the study team

2025-02-10

Who can join

Age: 10 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosed as metastatic carcinoma of the thoracolumbar spine
• solitary neoplasm involve only one segment of spine
• patients underwent separation surgery

You may not qualify if…

• coagulation function was abnormal preoperatively
• patients are allergic to tranexamic acid
• neoplasm involve more than one segment of spine
• patients with rich blood supply who need embolization

Where it is running

• the Second Affiliated Hospital Zhejiang University School of Medicine — Hangzhou, Zhejiang, China (enrolling)

Full record on ClinicalTrials.gov

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