Analysis of Varus Collapse in Obese Patients With Stem and Non-Stem Tibial Components Following Primary Total Knee Arthroplasty

Running, not enrolling · Not applicable

Conditions studied: Obesity, Aseptic Loosening, Varus Collapse

In brief

The purpose of this study is to compare rates of varus collapse, aseptic loosening, and implant failure in female obese patients undergoing total knee arthroplasty (TKA) and will review the degree of influence of stemmed tibial components versus non-stemmed tibial components on varus collapse and aseptic loosening, a consequence of implant micromotion.

Key facts

Study ID

NCT06019832

Run by

Jacob M. Elkins

People needed

54

Starts

2023-08-14

Expected to finish

2032-12-31

Last updated by the study team

2026-05-29

Who can join

Age: 40 and older, up to 99. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Female adult patients with severe osteoarthritis scheduled to have primary total knee arthroplasty
• Age 40 or older
• 35 kg/m2 and above
• Only patients from the PI's clinic will be included.
• Women who are still menstruating and are currently on contraceptives and women who are in menopause.

You may not qualify if…

• Patients who have some active local or widespread infection (including secondary or inflammatory osteoarthritis)
• medical conditions that put them at risk of complications or death during and after the study would not be eligible for surgery
• Patients with previous knee surgery on arthroplasty site will be excluded
• Pregnant patients and women who are capable of getting pregnant

Where it is running

• Iowa Health Care Medical Center North Liberty — North Liberty, Iowa, United States

Full record on ClinicalTrials.gov

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