HD-tDCS for Phonological Impairment in Aphasia

Running, not enrolling · Not applicable · Has a placebo group

Conditions studied: Aphasia, Stroke

In brief

This study will investigate the effects of mild electrical stimulation in conjunction with speech therapy for people with post-stroke aphasia to enhance language recovery.

Key facts

Study ID: NCT06010030
Run by: Medical College of Wisconsin
People needed: 200
Starts: 2023-10-03
Expected to finish: 2033-01-01
Last updated by the study team: 2026-03-13

Who can join

Age: 18 and older, up to 85. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

Patients must be 18 or older.
Patients may not be older than 85.
Patients must have a language deficit from left-sided focal neurologic damage (e.g. stroke, tumor).
Patients must be adults and have English-language fluency.
Patients must be eligible to undergo MRI.
Beyond meeting the inclusion criteria, no preference will be given on the basis of race, ethnicity or gender.

You may not qualify if…

Advanced neurodegenerative disease (i.e. Stage 3 Alzheimer's disease)
Neurologic disease (e.g. idiopathic epilepsy, seizure disorders that are not well managed, Parkinson's disease, ALS),
Severe psychopathology (e.g. schizophrenia, bipolar disorder, acute major depressive episode)
Suspected or diagnosed uncorrectable hearing or vision difficulties, or developmental disabilities (i.e. intellectual disability or learning disability).
Contraindications to MRI such as claustrophobia, implanted electronic devices, MRI-incompatible metal in the body, extreme obesity, pregnancy, inability to lie flat, inability to see or hear stimulus materials.
Younger than 18 or older than 85.
< 6 months post tumor resection.

Where it is running

Medical College of Wisconsin — Milwaukee, Wisconsin, United States

Full record on ClinicalTrials.gov

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