Evaluating the Impact of Social and Genetic Factors on Outcomes in Adolescent and Young Adult Cancer Survivors

Recruiting now

Conditions studied: Hodgkin Lymphoma, Non-Hodgkin Lymphoma

In brief

This study examines the impact of social and genetic factors on outcomes in adolescent and young adult (AYA) cancer survivors of Hodgkin or non-Hodgkin lymphoma. Compared to both older adult and childhood cancer patients, AYAs with cancer experience different diagnoses and specific biological, clinical, psychological and social factors that affect their risks for post-treatment morbidity and premature death. Collecting samples of blood samples and health and treatment information from cancer survivors of Hodgkin or non-Hodgkin lymphoma may help doctors identify conditions that increase the likelihood of AYAs getting sick and dying after treatment of cancer and better understand how to address the needs of adolescent and young adult cancer survivors.

Key facts

Study ID

NCT06002828

Run by

ECOG-ACRIN Cancer Research Group

People needed

2000

Starts

2023-10-13

Expected to finish

2030-02-01

Last updated by the study team

2026-06-18

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patient must be >= 18 years of age at the time of registration
• Patient must have been between the ages of 15-39 at the time of their first primary cancer diagnosis of Hodgkin lymphoma or non-Hodgkin lymphoma (NHL)
• Patient must have completed therapy (with a complete response, per clinician determination) at the time of registration
• Patients last date of prior systemic therapy for first primary diagnosis for Hodgkin lymphoma or non-Hodgkin lymphoma must have been within one year prior to registration
• NOTE: Systemic therapy refers to all anti-cancer therapy, including but not limited to chemotherapy, intravenous (IV) or oral targeted medications, or radiation, and administered via a clinical trial or standard approach
• Patient must have an Eastern Cooperative Oncology Group (ECOG) Performance Status of 0-3
• Patient must be English speaking in order to be able to complete the required QOL forms on this study
• NOTE: Sites cannot translate the associated QOL forms
• Patient must not be receiving active therapy for Hodgkin lymphoma or non-Hodgkin lymphoma
• Patient must have internet access through computer, tablet, or smartphone
• Patient must have email address
• Patient must have the ability to understand and the willingness to sign a written informed consent document. Patients with impaired decision-making capacity (IDMC) who have a legally authorized representative (LAR) or caregiver and/or family member available will also be considered eligible

Where it is running

• Rocky Mountain Cancer Centers-Boulder — Boulder, Colorado, United States (enrolling)
• Rocky Mountain Cancer Centers - Centennial — Centennial, Colorado, United States (enrolling)
• Rocky Mountain Cancer Centers-Aurora — Aurora, Colorado, United States (enrolling)
• Boulder Community Foothills Hospital — Boulder, Colorado, United States (enrolling)
• Anchorage Associates in Radiation Medicine — Anchorage, Alaska, United States (enrolling)
• Katmai Oncology Group — Anchorage, Alaska, United States (enrolling)
• Anchorage Radiation Therapy Center — Anchorage, Alaska, United States (enrolling)
• BASS Medical Group - Lennon — Walnut Creek, California, United States (enrolling)
• Alaska Women's Cancer Care — Anchorage, Alaska, United States (enrolling)
• Mercy Hospital Fort Smith — Fort Smith, Arkansas, United States (enrolling)
• Alaska Breast Care and Surgery LLC — Anchorage, Alaska, United States (enrolling)
• CARTI Cancer Center — Little Rock, Arkansas, United States (enrolling)
• PCR Oncology — Arroyo Grande, California, United States (enrolling)
• Providence Saint Joseph Medical Center/Disney Family Cancer Center — Burbank, California, United States (enrolling)
• Providence Alaska Medical Center — Anchorage, Alaska, United States (enrolling)
• Alaska Oncology and Hematology LLC — Anchorage, Alaska, United States (enrolling)
• Fairbanks Memorial Hospital — Fairbanks, Alaska, United States (enrolling)
• Contra Costa Regional Medical Center — Martinez, California, United States (enrolling)
• Providence Queen of The Valley — Napa, California, United States (enrolling)
• Kingman Regional Medical Center — Kingman, Arizona, United States (enrolling)
• Stanford Cancer Institute Palo Alto — Palo Alto, California, United States (enrolling)
• Providence Medical Foundation - Santa Rosa — Santa Rosa, California, United States (enrolling)
• Providence Santa Rosa Memorial Hospital — Santa Rosa, California, United States (enrolling)
• NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro — Jonesboro, Arkansas, United States (enrolling)
• The Women's Imaging Center — Denver, Colorado, United States (enrolling)

Full record on ClinicalTrials.gov

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