The Effect of Superficial Parasternal Intercostal Plane Block on Pulmonary Function Tests After Cardiac Surgery
Recruiting now · Not applicable
Conditions studied: Postoperative Pain, Pulmonary Function Tests
In brief
In adult patients undergoing cardiac surgery, does adding an sPIP block to standard care compared to standard care alone result in a smaller decrease in PFTs?
Key facts
- Study ID
- NCT05999721
- Run by
- Shai Fein
- People needed
- 100
- Starts
- 2025-01-25
- Expected to finish
- 2027-01-01
- Last updated by the study team
- 2026-07-09
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients who are scheduled to undergo elective cardiac surgery via sternotomy (i.e., coronary artery bypass graft, valvular surgery, and combined surgery).
- Body Mass Index (BMI) above 20 and below 40 kg m-2
- Age above 18 years.
- Eligible to sign informed consent.
You may not qualify if…
- Emergency surgery.
- Redo surgery.
- Off-pump surgeries.
- Pregnancy.
- Preoperative mechanical circulatory support (i.e., intra-aortic balloon pump, extracorporeal membrane oxygenation, ventricular assist devices).
- Preoperative chronic pain (i.e., fibromyalgia, chronic neuropathic pain).
- Contraindication for regional analgesia (i.e., known allergy to LA, skin lesions in the injection site).
- Known allergy to one or more of the components of multimodal analgesia (i.e., opioids, paracetamol, tramadol, dipyrone).
- Preexisting severe pulmonary disease (i.e., an obstructive lung disease with FEV1 below 49%, restrictive lung disease with FVC below 49%, pulmonary hypertension).
- Criteria For Discontinuing (Postoperative Exclusion Criteria):
- Prolonged cardiopulmonary bypass (CPB) of more than three hours.
- Transfusion of more than three units of blood products.
- Severe coagulation disturbance requiring prothrombin complex concentrate or recombinant factor VII.
- Left ventricular failure with vasoactive-inotropic score (VIS) at the end of the surgery of ≥ 20.
- Right ventricular failure requires inhaled nitric oxide.
- Need for mechanical circulatory support (i.e., intra-aortic balloon pump, extracorporeal membrane oxygenation).
- Patients requiring mechanical ventilation for more than 24 hours postoperatively.
Where it is running
- Rabin Medical Center, Beilinson Hospital — Petah Tikva, Israel (enrolling)
- Rabin Medical Center — Petah Tikva, Israel
Full record on ClinicalTrials.gov
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