99mTc-H7ND SPECT/CT Imaging in NSCLC

Recruiting now · Not applicable

Conditions studied: NSCLC

In brief

To study the clinical application of 99mTc-H7ND SPECT/CT imaging in the efficacy evaluation and prediction of non-small cell lung cancer (NSCLC)

Key facts

Study ID

NCT05999214

Run by

First Affiliated Hospital Xi'an Jiaotong University

People needed

150

Starts

2023-09-13

Expected to finish

2026-08-10

Last updated by the study team

2023-09-25

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients aged from 18 to 80 years old;
• patients with NSCLC confirmed by needle aspiration cytology or surgical pathology, who cannot undergo radical surgery due to recurrence, metastasis or patient's own conditions;
• Has completed 2-4 cycles of first-line therapy (including chemotherapy, immunotherapy, chemotherapy combined with immunotherapy, chemotherapy combined with targeted therapy, etc.), and has SD assessed by RECIST 1.1 during the same period;
• Patients had at least one measurable lesion;
• No local radiotherapy for primary or metastatic lesions within 28 days;
• ECOG score 0-2;
• Expected survival time ≥3 months;
• Voluntarily participate and sign informed consent.

You may not qualify if…

• Women who plan to become pregnant within 6 months, or are pregnant or lactating.
• Patients with severe brain or bone metastases;
• Severe anemia and severe liver and kidney damage;
• Pathological or long-term follow-up results may not be available;
• The relevant control imaging data and clinical data were not available;
• Severe illness is difficult to cooperate (such as acute cardiovascular and cerebrovascular events or serious cardiovascular diseases);
• Received any surgery or invasive treatment or procedure within 4 weeks before enrollment;
• Cannot tolerate standard second-line therapy or other first-line therapies.
• Known allergy to 99mTc-H7ND or any of its components; He had a history of severe allergies;
• Protocol imaging contraindications were present;
• The investigator considered it inappropriate to participate in the study.

Where it is running

• First Affiliated Hospital of Xi'an Jiaotong University — Xi'an, Shaanxi, China (enrolling)

Full record on ClinicalTrials.gov

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