Tobacco Cessation at FDNY

Completed · Phase 4

Conditions studied: Tobacco Use, Tobacco Smoking, Tobacco Use Cessation

In brief

At the Fire Department of the City of New York (FDNY) World Trade Center Health Program, 36% of participants in the low dose computed tomography (LDCT) lung cancer screening program are current smokers, despite referral to the free FDNY Tobacco Cessation Program (Standard Care). Investigators propose testing an Enhanced Care program which includes opt-out enrollment; tobacco cessation counseling will be individually tailored to spirometry/LDCT results and treatment with varenicline starting 4 weeks prior to their target quit date. This randomized trial will compare enrollment and cessation outcomes in Standard Care vs. Enhanced Care groups of challenging-to-treat, high-risk smokers.

Key facts

Study ID

NCT05997225

Run by

Albert Einstein College of Medicine

People needed

23

Starts

2024-05-31

Expected to finish

2025-10-13

Last updated by the study team

2026-01-29

Who can join

Age: 40 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Enrolled in FDNY World Trade Center Health Program (WTCHP)
• Retired
• Age ≥ 50 years old
• Self-reported current smoker on most recent questionnaire OR self-reported current smoker in the past 5 years
• 20 pack-year smoker OR 20-year smoking duration

You may not qualify if…

• Reduced renal function
• estimated glomerular filtration rate (eGFR) <30 [CKD-EPI Creatinine Equation (2021)] at last World Trade Center (WTC) medical monitoring blood exam OR ICD10 codes for kidney disease: N04.9, N17.9, N18.9, Z94.0, E13.21, N18.9, I12.9, N00.9, N03.9
• Undergoing active cancer treatment, defined as being diagnosed on 1/1/2022 or later
• Clinical instability (e.g., hospitalization in last 3 months)
• Using varenicline in last 30 days
• Endorsing suicidal ideations: moderate or high risk on Columbia-Suicide Severity Rating Scale (C-SSRS)
• Screened for alcohol use disorder AUDIT>15

Where it is running

• FDNY World Trade Center Health Program — Brooklyn, New York, United States

Full record on ClinicalTrials.gov

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