Non-pharmacological Prevention of POD in Frailty Elderly Undergoing Elective Surgery Applied by Nursing Teams
Recruiting now · Not applicable
Conditions studied: Frail Elderly Syndrome, Primary Prevention, Postoperative Delirium, Frailty
In brief
The increase in the population over 60 years of age who could receive surgery due to changes in life expectancy and advances in surgical and anesthetic techniques. Likewise, elderly people (EP) may have a higher risk of postoperative morbidity and mortality compared to young people, with frailty being one of the risk factors that increases adverse outcomes in this period and increases the probability of developing syndromes such as postoperative delirium (POD). Assessment of frailty in EP prior to surgery is not routine, so it is unknown how many frail and/or pre-frail EP undergo surgery in health care systems. There is an association between being frail and developing greater delirium and/or postoperative cognitive deficit, which in summary translates into an increase in perioperative morbidity and mortality. For the prevention of POD, there are pharmacological and non-pharmacological measures that seek to promote orientation with respect to their environment and make it as familiar as possible, stimulate early aspects of memory and thinking skills, as well as promote sleep using environmental hygiene measures. In Chile, protocols of non-pharmacological measures have been proposed by occupational therapy teams, which have had positive results in reducing POD in frail elderly patients. These measures are temporal-spatial reorientation, physical mobilization, correction of sensory deficits, environmental management, sleep protocol, and reduction of anticholinergic drugs with statistically significant results in the reduction of POD. In accordance with the above, the objective of this study is to evaluate the impact of non-pharmacological measures applied by the nursing team in reducing the incidence of POD during the post-surgical period in fragile and pre-fragile EP undergoing elective non-cardiac surgeries. It is expected that in the end, frail and pre-frail EP who receive non-pharmacological interventions by the nursing team will present a lower incidence of POD at 24 hours compared to those who receive traditional care.
Key facts
- Study ID
- NCT05993754
- Run by
- Pontificia Universidad Catolica de Chile
- People needed
- 400
- Starts
- 2024-04-01
- Expected to finish
- 2026-12-31
- Last updated by the study team
- 2025-06-10
Who can join
Age: 65 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients older than 65 years
- Elective non-cardiac surgery
- General anesthesia with Bilateral BIS electroencephalographic monitoring or SedLine
- ASA I, II or III.
You may not qualify if…
- Neurosurgical patients
- History of alcohol and/or drug abuse
- History of recreational psychoactive drug use
- Allergy to anesthetic drugs.
Where it is running
- Pontificia Universidad Catolica de Chile — Santiago, Santiago Metropolitan, Chile (enrolling)
Full record on ClinicalTrials.gov
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