Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1403 and mRNA-1405 to Prevent Norovirus Acute Gastroenteritis in Healthy Adults 18 to 80 Years of Age
Running, not enrolling · Phase 1/Phase 2 · Has a placebo group
Conditions studied: Norovirus Acute Gastroenteritis
In brief
The purpose of the Part A Phase 1 of this study is to evaluate the safety, reactogenicity, and immunogenicity of mRNA-1403 and mRNA-1405 in healthy adult participants 18 to 49 years of age and 60 to 80 years of age. The purpose of Part B Phase 2 and Part C Phase 2 is to evaluate the safety, reactogenicity, and immunogenicity of mRNA-1403 in healthy adult participants (18 to 80 years of age).
Key facts
- Study ID
- NCT05992935
- Run by
- ModernaTX, Inc.
- People needed
- 1407
- Starts
- 2023-08-25
- Expected to finish
- 2026-09-22
- Last updated by the study team
- 2026-04-03
Who can join
Age: 18 and older, up to 80. Sex: any. Healthy volunteers: accepted.
Where it is running
- ARK Clinical Research, LLC — Long Beach, California, United States
- Tekton Research, Inc - Longmont Center — Longmont, Colorado, United States
- Research Centers of America — Hollywood, Florida, United States
- Accel Research Sites Network — Decatur, Georgia, United States
- Velocity Clinical Research - Boise — Meridian, Idaho, United States
- Optimal Research — Peoria, Illinois, United States
- Velocity Clinical Research — Sioux City, Iowa, United States
- Johnson County Clin-Trials (JCCT) — Lenexa, Kansas, United States
- Velocity Clinical Research — Rockville, Maryland, United States
- Velocity Clinical Research — Norfolk, Nebraska, United States
- Velocity Clinical Research — Omaha, Nebraska, United States
- Rochester Clinical Research, Inc — Rochester, New York, United States
- Epic Medical Research, LLC — Red Oak, Texas, United States
- JBR Clinical Research — Salt Lake City, Utah, United States
- Emeritus Research Camberwell — Camberwell, Australia
- Nucleus Network — Melbourne, Australia
Full record on ClinicalTrials.gov
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