Multifaceted Comparison of Ultrasound-guided Ablation and Laparoscopic Adrenalectomy for Aldosterone-producing Adenoma
Recruiting now
Conditions studied: Aldosterone-producing Adenoma, Radiofrequency Ablation
In brief
The purpose of this study is to retrospectively and prospectively analyze the efficacy and safety of ultrasound-guided radiofrequency ablation and laparoscopic adrenalectomy in the treatment of aldosterone-producing adenoma (APA). It is planned to retrospectively collect 30 patients with adrenal radiofrequency ablation for APA and 15 patients with age - and sex-matched laparoscopic adrenalectomy for APA in our hospital from January 2020 to June 2024, and continue to follow up for 3 years.
Key facts
- Study ID
- NCT05991856
- Run by
- Third Affiliated Hospital, Sun Yat-Sen University
- People needed
- 45
- Starts
- 2020-01-01
- Expected to finish
- 2030-12-01
- Last updated by the study team
- 2023-08-15
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- APA was confirmed with unilateral lesions;
- Benign tumor without adrenal metastasis and endovascular tumor embolus;
- Receive ultrasound-guided adrenal RFA treatment or laparoscopic resection, and sign the informed consent for surgery;
- Age ≥ 18;
- Age ≥ 40 years old should meet the following criteria: blood potassium ≤3.5mmol/L; PAC≥20ng/dL; PRC≤5μIU/mL; A unilateral adrenal nodule of 10mm or more was completely normal on the opposite side.
You may not qualify if…
- Bilateral adrenal diseases;
- Multiple adrenal tumors;
- Other adrenal diseases, such as adrenal hyperplasia, Cushing's syndrome, pheochromocytoma, etc.;
- Imaging suggests that the tumor may be difficult to reach;
- Imaging showed potential malignant adrenal tumor;
- Pregnant and/or planning a pregnancy;
- Refusing to participate in follow-up visits.
Where it is running
- The Third Affiliated Hospital of Sun Yat-sen University — Guangzhou, Guangdong, China (enrolling)
Full record on ClinicalTrials.gov
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