Screening and Secondary Prevention Rheumatic Heart Disease Study

Recruiting now

Conditions studied: Rheumatic Heart Disease

In brief

After basic clinical screening including history and physical, Point of care ultrasound will be performed to look at Mitral, Aortic and Tricuspid Valves for regurgitation or stenosis. For patients with confirmed Rheumatic heart disease (RHD), treatment and referral depending on stage of disease. Antibiotic prescription could be shifted to community health workers delivering preventive medications via practical clinical algorithms, diagnostic tools, availability of appropriate antibiotics, and supportive supervision. Patients will have repeat imaging at 2 years and 5 years to look at the outcome of delayed progression of valve disease.

Key facts

Study ID

NCT05991219

Run by

National Institute of Cardiovascular Diseases, Pakistan

People needed

5000

Starts

2022-09-26

Expected to finish

2028-12-31

Last updated by the study team

2023-08-15

Who can join

Age: 10 and older, up to 30. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Rural communities in Sindh

You may not qualify if…

• Refused to participate in the study

Where it is running

• National Institute of Cardiovascular Diseases (NICVD) — Karachi, Sindh, Pakistan (enrolling)

Full record on ClinicalTrials.gov

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