Prevention of Anhedonia in Children
Completed · Not applicable
Conditions studied: Anhedonia, Depression
In brief
This trial will test the effects of a positive emotion-focused preventive intervention on reward responsiveness in children of mothers with histories of depression and anhedonia.
Key facts
- Study ID
- NCT05988138
- Run by
- Vanderbilt University
- People needed
- 73
- Starts
- 2023-11-10
- Expected to finish
- 2026-01-17
- Last updated by the study team
- 2026-07-09
Who can join
Age: 8 and older, up to 12. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Biological mothers with past or current MDD with anhedonia and their 8- to 12-year-old children
- Child and biological mother can read and speak fluently in English
- Child and mother have access to a computer or tablet and internet for videoconferencing
- For compensation purposes, child and biological mothers must be U.S. citizens
You may not qualify if…
- Children with past or current major depressive disorder (MDD) and/or anhedonia lasting most of the day, nearly every day for at least 2 weeks based on semi-structured interviews will be excluded
- Mothers or children with intellectual or developmental disabilities
- Mothers with past 6 months substance use disorder with moderate or greater severity
- Children or mothers with a lifetime history of a manic or hypomanic episode/bipolar disorder
- Children or mothers with a psychotic disorder (e.g., schizophrenia)
- Children or mothers with visual or hearing impairments that interfere with completing study measures and sessions
- Child offspring of a mother who has previously participated in the study with another biological child
- Children taking medications for emotional or behavioral problems other than SSRIs (stable dose for 6 weeks before time of enrollment) or psychostimulants
Where it is running
- Jesup/Hobbs Building — Nashville, Tennessee, United States
Full record on ClinicalTrials.gov
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