Ketamine Enhances Analgesia and Mood in Chronic Pain Patients

Recruiting now

Conditions studied: Mood Disorder; Opioid, Mood Insomnia

In brief

Most chronic pain patients have mood disorders. The mood disorders may improve with better analgesia produced by Ketamine injections. A prospective study of patients undergoing interventional pain therapy using Ketamine injections. Pre-injection and post-injection patient data is collected. Pain is measured using numeric pain rating scale, and change in pain score by 2-points is considered significant. Sleep is measured using Likert sleep scale, and change in sleep score by 2-points is considered significant. Anxiety is measured using general anxiety disorder (GAD-7) scale, and change in anxiety score by 4-points is considered significant. Depression is measured using patient health questionnaire (PHQ-9), and change in depression score by 5-points is considered significant.

Key facts

Study ID

NCT05985811

Run by

Salem Anaesthesia Pain Clinic

People needed

500

Starts

2018-02-02

Expected to finish

2025-12-31

Last updated by the study team

2025-01-27

Who can join

Age: 20 and older, up to 99. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• adult chronic pain patients
• associated mood disorder
• good treatment compliance
• associated chronic insomnia
• regular ketamine pain therapy injection
• consent for clinical record quality assurance review

You may not qualify if…

• severe cognitive disorder
• inability to provide consent
• major neuropsychiatric disorder
• cannabis use
• stimulant use
• substance abuse
• poor treatment compliance
• lack of ketamine pain therapy injection

Where it is running

• Salem Anaesthesia Pain Clinic — Surrey, British Columbia, Canada (enrolling)

Full record on ClinicalTrials.gov

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