Bone Marrow Aspirate Concentrate (BMAC) vs Corticosteroid Injection

Recruiting now · Not applicable · Has a placebo group

Conditions studied: Osteoarthritis of the Knee

In brief

Prospective single-masked (study participant will be masked), randomized controlled trial to examine the influence of BMAC on patient-reported outcomes (PROs) in patients with primary knee osteoarthritis.

Key facts

Study ID

NCT05985785

Run by

Rush University Medical Center

People needed

100

Starts

2022-07-19

Expected to finish

2028-03-31

Last updated by the study team

2025-08-13

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients between the ages of 18-70
• Long standing knee pain from osteoarthritis (KL grade 2-3) despite conventional treatments such as activity modification, weight loss, physical therapy, analgesics, nonsteroidal anti-inflammatory drugs, or injection therapy for at least 6 weeks
• 7-day average pain score of at least 4 on VAS scale

You may not qualify if…

• Systemic diseases (Diabetes, malignancies, infections, etc.)
• Post-traumatic arthritis
• Patient had intra-articular injection on affected knee in last three months

Where it is running

• Rush University Medical Center — Chicago, Illinois, United States (enrolling)

Full record on ClinicalTrials.gov

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