Study to Assess GTAEXS617 in Participants With Advanced Solid Tumors
Recruiting now · Phase 1/Phase 2
Conditions studied: Head and Neck Squamous Cell Carcinoma (HNSCC), Pancreatic Adenocarcinoma, Non-small Cell Lung Cancer (NSCLC), Platinum-resistant High-grade Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancers (HGSOC), Hormone Receptor Positive [HR+] and Human Epidermal Growth Factor Receptor 2 Negative [HER2-] Breast Carcinoma, Triple Negative Breast Cancer (TNBC)
In brief
The primary purpose of this study is to assess the safety, tolerability, pharmacokinetics (PK) and anti-tumor activity of GTAEXS617 (REC-617) in participants with advanced solid tumors.
Key facts
- Study ID
- NCT05985655
- Run by
- Exscientia AI Ltd., a wholly owned subsidiary of Recursion Pharmaceuticals, Inc.
- People needed
- 230
- Starts
- 2023-07-06
- Expected to finish
- 2028-05-01
- Last updated by the study team
- 2026-04-23
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- USC Norris Comprehensive Cancer Center — Los Angeles, California, United States (enrolling)
- START Midwest — Grand Rapids, Michigan, United States (enrolling)
- START San Antonio — San Antonio, Texas, United States (enrolling)
- START Mountain Region — West Valley City, Utah, United States (enrolling)
- GZA Ziekenhuizen - Campus Sint-Augustinus — Antwerp, Belgium (enrolling)
- Clinique Universitaires Saint-Luc — Brussels, Belgium (enrolling)
- Institute Jules Bordet — Brussels, Belgium (enrolling)
- CHU Sart Tilman — Liège, Belgium (enrolling)
- The Beatson West of Scotland Cancer Centre — Glasgow, United Kingdom (enrolling)
- UCL Hospitals NHS Foundation Trust — London, United Kingdom (enrolling)
- The Christie NHS Foundation Trust — Manchester, United Kingdom (enrolling)
- Newcastle Upon Tyne NHS Foundation Trust — Newcastle upon Tyne, United Kingdom (enrolling)
- Oxford University Hospitals NHS Foundation Trust — Oxford, United Kingdom (enrolling)
Full record on ClinicalTrials.gov
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