Effect of High Velocity/Hyperoxic Breathing Therapy on Blood Lactate Decline

Completed · Not applicable

Conditions studied: Dyspnea, Lactic Acidosis, Muscle, Breathlessness, Exercise, Recovery

In brief

The study will evaluate the impact of high velocity therapy (HVT) on reduction of work of breathing (as implied by breath frequency) and enhanced blood lactate decline during recovery from a Wingate-type Exercise test. The study will include four study segments, corresponding to four different therapy settings.

Key facts

Study ID: NCT05984186
Run by: Vapotherm, Inc.
People needed: 15
Starts: 2023-03-06
Expected to finish: 2023-12-31
Last updated by the study team: 2024-10-08

Who can join

Age: 18 and older, up to 30. Sex: any. Healthy volunteers: accepted.

You may qualify if…

Adults18-30 years old, in a general state of good health, of either sex
No known contraindication to performing a maximal exercise test, i.e., Wingate-type Anaerobic exercise test
Participants must consider themselves able to perform "regular moderate" or "regular strenuous" exercise.
° "Regular moderate" exercise includes less than 30 minutes every day or 30 minutes every other day, of some form of deliberate exercise, that does not include walking.
° "Regular strenuous" exercise is 30+ minutes per day, of some form of deliberate exercise, that does not include walking.

You may not qualify if…

Not considered a 'high-performance athlete'
Known active cardiovascular, metabolic, liver, or renal disease
Orthopedic limitations to exercise
Pregnancy
Use of beta-blockers or beta-agonist asthma medications
Exercise induced asthma
Any other health-related issue that would involve the participant's fitness capability
Inability to complete all of the study procedures

Where it is running

Auburn University — Auburn, Alabama, United States

Full record on ClinicalTrials.gov

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