Prism Adaptation Therapy (PAT) for Right Brain Stroke Rehabilitation

Recruiting now · Not applicable

Conditions studied: Spatial Neglect After Right Brain Stroke

In brief

After a right brain stroke, \>50% of Veterans experience problems with dressing, eating, self-care or steering their wheelchairs because their ability to move, orient, and respond toward the left side is limited: spatial neglect. Spatial neglect prevents them from functioning independently, and their needs in the hospital and at home are greatly increased. An effective treatment for spatial neglect is 10 days of visuomotor training while wearing optical prisms (PAT), however many clinicians \[fail to diagnose spatial neglect and use this approach. In this study, the investigators will develop a brain scanning test that could objectively identify the Veterans with spatial neglect after stroke who are the best candidates to receive PAT and recover their ability to function. When the research is complete, the investigators expect that brain scans done in the hospital can guide the team to refer Veterans to PAT rehabilitation: improving daily life function\] and quality of life.

Key facts

Study ID

NCT05983185

Run by

VA Office of Research and Development

People needed

244

Starts

2023-02-01

Expected to finish

2027-12-31

Last updated by the study team

2026-04-23

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Has had a first right brain stroke >18 years of age
• 1-4 months post-diagnosis of right brain stroke
• Can sit up, see out of both eyes and point to objects (>20/50 vision in both eyes)
• Can give informed consent to participate

You may not qualify if…

• Has been diagnosed with other chronic, disabling neurological disorder (e.g. multiple sclerosis, Alzheimer Disease)
• Has had a clinical left brain stroke or has neuroimaging evidence of prior stroke(s) including the presence of more than two lacunes with diameter greater than 15 mm.
• Cannot sit up to be tested and receive PAT
• Has <20/50 vision when viewing with both eyes

Where it is running

• VA Connecticut Healthcare System West Haven Campus, West Haven, CT — West Haven, Connecticut, United States (enrolling)
• Atlanta VA Medical and Rehab Center, Decatur, GA — Decatur, Georgia, United States (enrolling)
• VA Central Western Massachusetts Healthcare System, Leeds, MA — Leeds, Massachusetts, United States (enrolling)
• Louis Stokes VA Medical Center, Cleveland, OH — Cleveland, Ohio, United States (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.