Epidural Electrical Stimulation for Stroke Patients - Improve Motor and Sensory Function and Alleviate Pain

Recruiting now · Not applicable

Conditions studied: Stroke

In brief

This study aims to verify whether epidural electrical stimulation (EES) of the cervical spinal cord can activate muscles of the upper limbs in people with hemiplegia following a stroke.

Key facts

Study ID: NCT05981989
Run by: Buddhist Tzu Chi General Hospital
People needed: 20
Starts: 2023-04-01
Expected to finish: 2026-12-31
Last updated by the study team: 2025-09-19

Who can join

Age: 20 and older, up to 70. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

Between 20 and 70 years of age
First-ever clinical manifest stroke
Right or left hemiparesis
Scores higher than 7 and lower than 45 on the Fugl-Meyer scale.
Expected will undergo spinal cord stimulation surgery.
Able to comply with procedures and follow up.
Stable medical condition without cardiopulmonary disease or dysautonomia that would contraindicate participation in upper extremity rehabilitation or testing activities.

You may not qualify if…

Pregnancy or breast feeding.
Have Major depressive disorder.
Had a mental illness within one year or been treated in the past.
Have significant cognitive impairment (MMSE<24) or serious disease that could affect the ability to participate in study activities.
Cardiovascular or musculoskeletal disease or injury that would prevent full participation in physical therapy intervention.
Receiving anticoagulant, anti-spasticity or anti-epileptic medications prior to or throughout the duration of the study.
Unable to read and/or comprehend the consent form.
Have concerns about this trial and do not sign consent.
Presence of joint contractures deemed by study clinician/investigator to be too severe to participate in study activities.

Where it is running

Buddhist Tzu Chi Medical Foundation Hualien Tzu Chi Hospital — Hualien City, Taiwan (enrolling)

Full record on ClinicalTrials.gov

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