Social Feedback and Dysfunctional Risk Taking in NSSI Adolescents

Recruiting now

Conditions studied: Nonsuicidal Self Injury, Risk-Taking

In brief

Nonsuicidal self-injury (NSSI) is defined as direct, intentional physical injury without suicidal intention. Problematic interpersonal relationships and decision-making have been demonstrated to play crucial roles in this maladaptive behavior, especially for adolescents. Accumulating evidence suggests that decision processes and risk-taking are strongly influenced by the affective state of the individual. However, whether these interactions are disrupted in NSSI adolescents has not been systematically examined. In the current study, the investigators modified one of the most widely used paradigms for measuring an individual's risk decision-making, the Balloon Analogue Risk Task (BART). The investigators combine social reward (green balloon), punishment (red balloon), and control feedback (yellow balloon), to investigate whether the NSSI adolescents have dysfunctional risk-taking behavior while facing different social outcomes. The investigators recruit one group of NSSI adolescents (n = 40) and one health control (HC) group (n = 40), to compare their risk-related decisions during the emotional BART. The investigators hypothesize that compared to HC, NSSI adolescents will show altered effects of social reward and punishment on risk-related decision-making, in particular higher risk avoidance in the context of social punishment.

Key facts

Study ID

NCT05981677

Run by

University of Electronic Science and Technology of China

People needed

80

Starts

2023-12-06

Expected to finish

2027-07-01

Last updated by the study team

2024-04-11

Who can join

Age: 15 and older, up to 18. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• 15-18 years
• right-handed
• normal or corrected normal visual acuity
• meet the proposed DSM-5 frequency criteria (e.g., ≥5 days of NSSI behaviors in the past year)

You may not qualify if…

• diagnosis of borderline personality disorder, major depressive disorder, other
• psychiatric disorders, etc.
• high suicidal risk
• recent use of medications that can affect neural activity
• have received or are receiving Dialectical Behavior Therapy (DBT) other treatment for emotional problems within the past 6 months
• have a contraindication to MRI scanning (e.g., metal implants, claustrophobia or other conditions that make them inappropriate for MRI scanning)

Where it is running

• Sichuan Provincial Center for Mental Health, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China — Chengdu, Sichuan, China (enrolling)

Full record on ClinicalTrials.gov

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