Effect of Ocrelizumab on Choroid Plexus Changes in Patients With PPMS

Completed

Conditions studied: Primary Progressive Multiple Sclerosis

In brief

The goal of this non-interventional, observational study is to learn if cortical plexus enhancement in patients with primary progressive multiple sclerosis occurs in response to the autoimmune inflammatory process.

Key facts

Study ID

NCT05974852

Run by

State University of New York at Buffalo

People needed

732

Starts

2023-10-01

Expected to finish

2023-12-30

Last updated by the study team

2026-03-09

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patient participating in the ORATORIO study
• MRI scans available at baseline
• Presence of T2-weighted image (WI) (FLAIR, T2/PD), and 3D T1-WI at baseline

You may not qualify if…

• None

Where it is running

• Buffalo Neuroimaging Analysis Center — Buffalo, New York, United States

Full record on ClinicalTrials.gov

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