Physiologic Cardiac Pacing to Prevent Left Ventricular Dysfunction Post TAVI

Recruiting now · Not applicable

Conditions studied: Atrioventricular Block, Second and Third Degree

In brief

The study aims to compare permanent Conduction System Pacing (CSP) with the standard therapy - Right Ventricular Pacing (RVP) or Biventricular Pacing (BVP) - in preventing the development and progression of symptomatic Chronic Heart Failure (CHF) and improving survival in patients after Transcatheter Aortic Valve Implantation (TAVI).

Key facts

Study ID

NCT05966675

Run by

Medical University of Silesia

People needed

500

Starts

2024-02-27

Expected to finish

2028-06-01

Last updated by the study team

2025-06-08

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• transcatheter aortic valve implantation (TAVI) in up to 30 days before qualification to pacemaker implantation
• Fulfilled criteria for permanent pacemaker implantation according do 2021 ESC guidelines
• Written informed consent
• Age of at least 18 years

You may not qualify if…

• Permanent pacemaker implantation before TAVI procedure
• The occurrence of conduction disturbances more than 30 days after TAVI procedure
• No written informed consent
• Inability to obtain informed consent from participant
• Predicted inability to obtain cooperation from patient during observation period

Where it is running

• Medical University of Silesia in Katowice — Katowice, Poland (enrolling)

Full record on ClinicalTrials.gov

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