Brain, Psychological and Epigenetic Determinants for Optimizing the Treatment of Chronic Low Back Pain

Recruiting now

Conditions studied: Chronic Low-back Pain

In brief

The goal of this observational study is to better understand the role of the brain in chronic low back pain patients.

Key facts

Study ID

NCT05963451

Run by

Université de Sherbrooke

People needed

80

Starts

2023-09-07

Expected to finish

2027-07-16

Last updated by the study team

2023-09-13

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Low back pain (≥ 6 months) with or without pain radiating to the legs or radiating to the neck
• Positive medial branch blocks, suggesting that the pain originates from the lumbar facet joints
• Average pain intensity of ≥ 3/10 in the 24-hour period before the initial visit
• Pain primarily localized in the lower back

You may not qualify if…

• Inadequate pain relief or relief of less than three months following selective thermoablation of medial lumbar branches by radiofrequency
• Neurological, cardiovascular, or pulmonary disorders
• Comorbid pain syndrome
• History of surgical intervention in the back
• A corticosteroid infiltration within the past year
• Pregnancy (current or planned during the course of the study)
• Contra-indication to Magnetic Resonance Imaging (MRI)

Where it is running

• Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke (CRCHUS) — Sherbrooke, Quebec, Canada (enrolling)

Full record on ClinicalTrials.gov

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