Passive Heat Therapy for People With COPD

Recruiting now · Not applicable · Has a placebo group

Conditions studied: COPD, Cardiovascular Diseases

In brief

People with Chronic Obstructive Pulmonary Disease (COPD) often develop high blood pressure and heart disease due to their sedentary lifestyle and difficulty exercising. The investigators will test if heating can mimic the health benefits of exercise by monitoring the increase in leg blood-flow using ultrasound during a 45-minute hot-water footbath. The patients will then undergo 6-weeks of hot-water footbaths to examine whether the changes to blood-flow lead to improvements in blood pressure and other indicators of heart disease risk.

Key facts

Study ID

NCT05962164

Run by

University of British Columbia

People needed

32

Starts

2023-08-17

Expected to finish

2026-05-31

Last updated by the study team

2025-04-04

Who can join

Age: 40 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Non-smoking individuals
• >40 years of age
• Stable (exacerbation free for >6 weeks), moderate-to-severe COPD (post bronchodilator FEV1/FVC <lower limit of normal and FEV1 z-score <2.51)

You may not qualify if…

• Performing structured exercise training (i.e. pulmonary rehabilitation)
• Have advanced cardiac or cerebrovascular disease (i.e. a history of heart failure, previous stroke or myocardial infarction)
• Have uncontrolled hypertension (>160/95 mmHg at rest)
• Have hypotension (<110/60 mmHg)
• Are taking Beta Blockers
• Regularly (>1/week) have hot baths (>30 min) or use a hot tub or sauna.
• Exclusion Criteria for exercise outcomes:
• Have resting blood pressure > 150/95 mmHg
• On supplemental oxygen for hypoxemia.
• Musculoskeletal pain that limits their ability to perform stationary cycling.

Where it is running

• University of British Columbia — Kelowna, British Columbia, Canada (enrolling)

Full record on ClinicalTrials.gov

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