Phase 1 Study to Determine the Metabolism and Clearance of Baxdrostat

Completed · Phase 1

Conditions studied: Hypertension

In brief

This was a Phase 1, open-label, single dose study in healthy male subjects. The goals of this clinical trial were to determine how baxdrostat might be absorbed and metabolized using radioactive \[14C\] labeled baxdrostat. Subjects were administered a single oral dose of 10 mg containing approximately 100 μCi of \[14C\] baxdrostat. Subjects were to be confined to the study site for 9 to 15 days for blood, urine, and feces collections.

Key facts

Study ID
NCT05961384
Run by
AstraZeneca
People needed
8
Starts
2021-11-18
Expected to finish
2022-01-15
Last updated by the study team
2023-08-15

Who can join

Age: 18 and older, up to 55. Sex: male. Healthy volunteers: accepted.

Where it is running

Full record on ClinicalTrials.gov

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