Effects of Remote Ischemic Preconditioning on Peripheral Blood Biomarkers in Healthy Adults (EMINENT)

Recruiting now · Not applicable

Conditions studied: Ischemic Preconditioning

In brief

The aim of this study is to investigate the effects of remote ischaemic preconditioning on the peripheral blood characteristics of healthy adults and to explore the possible mechanisms for improving ischaemia/reperfusion injury and its protective effects on the cardiovascular system.

Key facts

Study ID

NCT05957523

Run by

First Affiliated Hospital Xi'an Jiaotong University

People needed

80

Starts

2024-06-27

Expected to finish

2026-10-31

Last updated by the study team

2026-07-21

Who can join

Age: 18 and older, up to 45. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Aged 18 to 45 years;
• Be in good health;
• Consent to participate in the clinical trial and sign the informed consent form.

You may not qualify if…

• Abnormal results in biochemical checks and physiological indicators.
• Cardiovascular and cerebrovascular diseases: hypertension, coronary heart disease, congenital heart disease, cerebrovascular alterations, etc.
• Endocrine diseases: diabetes, thyroid disorders, etc.
• Hematologic diseases: anemia, paroxysmal hemoglobinuria, primary thrombocytosis, etc.
• Infectious diseases: hepatitis B, hepatitis C, syphilis, etc.
• Cancer.
• Neurological and psychiatric disorders.
• Vascular diseases: peripheral vascular disease, Raynaud's syndrome, thromboembolic diseases.
• Major trauma or surgery within the last six months.
• Pregnant or breastfeeding women.
• Upper limbs unsuitable for compression treatment: history of upper limb surgery, presence of tissue damage and limb deformity, and concomitant hemorrhagic diseases.
• Recent circumstances that may affect results: blood donors within the last month, any medication taken within the last month, fever within the last week, women within their menstrual cycle or within 7 days before the start of menstruation.
• Patients who refuse to sign the informed consent form for participation in this study.

Where it is running

• First Affiliated Hospital of Xian Jiantong University — Xi'an, Shaanxi, China (enrolling)

Full record on ClinicalTrials.gov

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