Supercharged TRAM Evaluation in Cervical Esophagogastroplasty After Esophagectomy

Recruiting now · Not applicable

Conditions studied: Esophagus Cancer, Carcinoma Esophagus

In brief

Esophagectomy has high rates of morbidity and mortality, in many cases due to esophagus reconstruction. Anastomotic leakage and fistula are the main esophagectomy complications. Many studies underwent to investigate the cause for anastomotic leakage after esophagectomy, however none of them conclude it is related to surgery or suture technique. However, it seems to be triggered by the ischemia caused after stomach mobilization to esophagus reconstruction, or even tension in the anastomosis. Considering the post esophagectomy with gastroplasty high morbidity and mortality rates, strategies to create a new vascularization source and decrease anastomotic leakage rates is important. In this study researchers will evaluate whether a TRAM flap transfer supercharged is effective on decrease morbidity related to anastomosis ischemia in patients undergoing esophagectomy.

Key facts

Study ID

NCT05954702

Run by

Instituto do Cancer do Estado de São Paulo

People needed

60

Starts

2023-07-21

Expected to finish

2026-10-01

Last updated by the study team

2023-10-16

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosis of esophageal malignancy cancer;
• Ability to understand and collaborate during treatment;

You may not qualify if…

• Previous gastrectomy;
• Previous abdominal surgery with risk of altering stomach vascularization;
• Previous head and neck surgery with risk of alteration of cervical vessels.

Where it is running

• Instituto do Cancer do Estado de São Paulo (ICESP) — São Paulo, São Paulo, Brazil (enrolling)

Full record on ClinicalTrials.gov

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