A First-in-Human (FIH) Study to Evaluate the Safety and Tolerability of VVD-130037 in Participants With Advanced Solid Tumors
Recruiting now · Phase 1
Conditions studied: Advanced Solid Tumors
In brief
A FIH dose escalation and dose expansion study to evaluate VVD-130037 in participants with advanced solid tumors as a single agent, and in combination with docetaxel, paclitaxel, or pembrolizumab.
Key facts
- Study ID
- NCT05954312
- Run by
- Vividion Therapeutics, Inc.
- People needed
- 290
- Starts
- 2023-07-28
- Expected to finish
- 2031-02-28
- Last updated by the study team
- 2026-05-08
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Mayo Clinic Jacksonville — Jacksonville, Florida, United States (enrolling)
- Florida Cancer Specialists — Sarasota, Florida, United States (enrolling)
- Moffitt Cancer Center — Tampa, Florida, United States (enrolling)
- Mayo Clinic Rochester — Rochester, Minnesota, United States (enrolling)
- Sarah Cannon Research Institute — Nashville, Tennessee, United States (enrolling)
- MDACC — Houston, Texas, United States (enrolling)
- NEXT Dallas — Irving, Texas, United States (enrolling)
- NEXT Virginia — Fairfax, Virginia, United States (enrolling)
- National Cancer Center — Goyang, South Korea (enrolling)
- The Catholic University of Korea, St. Vincent's Hospital — Goyang, South Korea (enrolling)
- Gachon University Gil Medical Center — Incheon, South Korea (enrolling)
- Seoul National University; Bundang Hospital — Seongnam, South Korea (enrolling)
- Asan Medical Center — Seoul, South Korea (enrolling)
- Samsung Medical Center — Seoul, South Korea (enrolling)
- Seoul National University Hospital — Seoul, South Korea (enrolling)
- Severance Hospital; Yonsei University Health System — Seoul, South Korea (enrolling)
- The Catholic University of Korea, St. Vincent's Hospital — Suwon, South Korea (enrolling)
- Hospital Vall d'Hebron — Barcelona, Spain (enrolling)
- START Barcelona Hospital HM Nou Delfos — Barcelona, Spain (enrolling)
- Hospital Universitario 12 de Octubre — Madrid, Spain (enrolling)
- Hospital Universitario Ramon y Cajal — Madrid, Spain (enrolling)
- NEXT Madrid — Madrid, Spain (enrolling)
- START Madrid CIOCC — Madrid, Spain (enrolling)
- Start Madrid-FJD, Hospital Fundacion Jimenez Diaz — Madrid, Spain (enrolling)
- Clinica Universitaria de Navarra — Pamplona, Spain (enrolling)
Full record on ClinicalTrials.gov
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