Presacral Nerve Block Versus Sham Block on Post-operative Pain for Total Laparoscopic Hysterectomy

Recruiting now · Phase 2 · Has a placebo group

Conditions studied: Post-operative Pain

In brief

The study is a single-center parallel group randomized controlled trial comparing the administration of a presacral nerve block using 20mL of local ropivacaine 5.0mg/ml versus 20mL of normal saline (sham block) on post-operative pain following total laparoscopic hysterectomy.

Key facts

Study ID

NCT05953766

Run by

Mount Sinai Hospital, Canada

People needed

60

Starts

2025-09-24

Expected to finish

2026-07-01

Last updated by the study team

2026-04-06

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• 18 years of age or older
• Undergoing total laparoscopic hysterectomy

You may not qualify if…

• Previous presacral neurectomy
• Concurrent surgical procedure other than salpingectomy and/or oophorectomy
• Gynecological cancer beyond stage 1 disease
• BMI > 50
• Chronic opioid consumption
• Fibromyalgia
• Language barrier
• Inability to communicate and provide consent

Where it is running

• Mount Sinai Hospital — Toronto, Ontario, Canada (enrolling)

Full record on ClinicalTrials.gov

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