Reducing Postoperative Opioids in Patients Undergoing Laparoscopic Hiatal Hernia

Completed · Not applicable

Conditions studied: Hiatal Hernia

In brief

This is a prospective randomized, double-blinded, controlled trial that will enroll 75 subjects undergoing laparoscopic hiatal hernia repair surgery. Participants who meet eligibility criteria will be randomized in a 1:1 ratio to receive either the opioid sparring anesthesia protocol (OSA) or the opioid based anesthesia protocol (OBA). The purpose of this study is to investigate if an opioid sparring protocol for laparoscopic hiatal hernia repair will reduce opioid consumption during discharge. Other outcomes include: postoperative VAS scores (PACU arrival, PACU discharge, hospital discharge), total in hospital opioid consumption, PACU length of stay, incidence of postoperative nausea and vomiting (PONV in PACU, postoperative day 1, during hospital stay), rehospitalization rate, rate of reoperation, rate of emergency room visit, surgeon satisfaction, and hospital cost differential.

Key facts

Study ID

NCT05953428

Run by

Endeavor Health

People needed

50

Starts

2023-11-14

Expected to finish

2026-04-30

Last updated by the study team

2026-05-06

Who can join

Age: 18 and older, up to 90. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Patients from 18-90 years old who are undergoing laparoscopic hiatal hernia surgery
• Elective Laparoscopic hiatal hernia repair

You may not qualify if…

• Patients receiving urgent or emergent hiatal hernia surgery
• Patients receiving hiatal hernia surgery without laparoscopy
• Patients with adverse reactions (e.g., anaphylaxis, rash) to any of the drugs in the OBA or OSA protocols.

Where it is running

• Endeavor Health — Evanston, Illinois, United States

Full record on ClinicalTrials.gov

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