Analysis of the Resistance and Sensitivity Mechanisms to Teclistamab by Focusing on Single Immune Cell Examination

Recruiting now · Not applicable

Conditions studied: Multiple Myeloma

In brief

The aim of this study is to discover the immune and oncogenomic features that distinguish patients who respond to teclistamab from patients who are primarily resistant. Moreover, phenotypic and genotypic characteristics that occur with secondary resistance to teclistamab will be analyzed.

Key facts

Study ID

NCT05945524

Run by

University Hospital, Toulouse

People needed

100

Starts

2023-09-28

Expected to finish

2026-05-31

Last updated by the study team

2025-04-10

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• With multiple myeloma
• Who receive Teclistamab
• Consent form signed

You may not qualify if…

• Patient under legal protection

Where it is running

• CHU d'Amiens — Amiens, France, France (enrolling)
• CHU de Caen — Caen, France, France (enrolling)
• Polyclinique du Parc Drevon — Dijon, France, France (enrolling)
• CH Annecy Genevois — Epagny Metz- Tessy, France, France (enrolling)
• CHU de Lille — Lille, France, France (enrolling)
• Centre Léon Bérard — Lyon, France, France (enrolling)
• CHU de Montpellier — Montpellier, France, France (enrolling)
• Hôpital Saint-Louis — Paris, France, France (enrolling)
• Hôpital Saint-Antoine — Paris, France, France (enrolling)
• Hôpital Necker — Paris, France, France (enrolling)
• CHU de Bordeaux — Pessac, France, France (enrolling)
• CHU de Lyon — Pierre-Bénite, France, France (enrolling)
• CHU de Poitiers — Poitiers, France, France (enrolling)
• CHU de Rennes — Rennes, France, France (enrolling)
• CH Saint-Etienne — Saint-Priest-en-Jarez, France, France (enrolling)
• CHU de Toulouse — Toulouse, France, France (enrolling)
• CHU de Tours — Tours, France, France (enrolling)
• CHRU Nancy — Vandœuvre-lès-Nancy, France, France (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.