Comparison of Rate of Complete Abortion Between Letrozole Plus Misoprostol vs Misoprostol Alone

Recruiting now · Not applicable

Conditions studied: Medical; Abortion, Fetus

In brief

Comparison of rate of complete abortion between Letrozole plus Misoprostol versus Misoprostol alone in first trimester pregnancy

Key facts

Study ID

NCT05940233

Run by

Queen Savang Vadhana Memorial Hospital, Thailand

People needed

70

Starts

2023-06-30

Expected to finish

2025-05-30

Last updated by the study team

2024-11-06

Who can join

Age: any. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Diafnoed Early pregnancy loss by TVS according to ACOG Practice bulletin 2018
• GA <= 14 weeks
• Os open <= 1 cm and no conceptus per os
• Hematicrit >= 30
• Systolic blood pressure >= 95 mmHg
• Informed consent done and can follow up and comunicate in Thai language

You may not qualify if…

• Allerguc to Letrozole or Misoprostol
• Intrauterine contraceptive device use
• Breast feeding
• Diagnoed with ectopic pregnancy or undiagnoed adnexal mass
• Severe or recurrent liver disease or AST or ALT more than or equal to 3 times of upper normal limit
• Multiple pregnancy
• Myoma uteri that involves the endometrium ex. Submucous myoma uteri
• Thromboembolism or has a history of thromboembolism
• Serum creatinine >= 2

Where it is running

• Sutinee Srimahachota — Bangkok, Yannawa, Thailand (enrolling)

Full record on ClinicalTrials.gov

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