MOS Prebiotic Potential in Older Adults

Running, not enrolling · Not applicable

Conditions studied: Healthy

In brief

Mannooligosaccharides (MOS) derived from baker's yeast may have prebiotic properties such as improving gastrointestinal function. The aims of this study are to determine the effect of MOS on gastrointestinal function and symptoms and fecal microbiota in older adults.

Key facts

Study ID

NCT05939336

Run by

University of Florida

People needed

40

Starts

2023-08-01

Expected to finish

2026-06-30

Last updated by the study team

2026-01-09

Who can join

Age: 50 and older, up to 99. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Adults 50-99 years of age.
• Able to provide written informed consent in English.
• Willingness to complete all study procedures
• Healthy or diagnoses with Parkinson's or multiple system atrophy

You may not qualify if…

• Yeast allergy.
• Self-reported kidney disease.
• Elite athletes or long-distance runners.
• Use of antibiotic drugs (e.g., neomycin, rifaximin) within 1 month of the screening visit.
• Current use of laxatives or antidiarrheal medications.
• Use of other investigational products within 3 months of the screening visit.
• Previously or currently being treated for any intestinal disease or condition, including IBS, Crohn's disease, ulcerative colitis, celiac disease, or gastrointestinal cancer (self-report).
• Previous gastrointestinal surgery (e.g., gastric bypass, fundoplication, bowel resection)
• Current cancer treatment
• Currently pregnant

Where it is running

• Food Science and Human Nutrition Department, University of Florida — Gainesville, Florida, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.