Mesenchymal Stem Cells Treatment for AIDS Patients at Late Stage

Recruiting now · Phase 1/Phase 2 · Has a placebo group

Conditions studied: AIDS

In brief

The goal of this study is to conduct a prospective, double-blind, randomized placebo-controlled clinical trial to investigate the safety and efficacy of mesenchymal stem cells treatment for AIDS patients at late stage.

Key facts

Study ID

NCT05939167

Run by

Cell Energy Life Sciences Group Co. LTD

People needed

150

Starts

2023-12-10

Expected to finish

2028-07-10

Last updated by the study team

2025-08-12

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Confirmed HIV infection, aged 18-65, both genders
• CD4+T count less than 500 cells/ul at baseline.
• No serious AIDS related events. 3. could understand and sign the informed consent form and comply with the requirements of this study.
• agree not to participate in other studies and not to receive other immunotherapies during the period of participation in this study

You may not qualify if…

• have HBV/HCV/HDV/HEV infection, and the virological test is positive.
• The viral load for CMV and EBV is more than 1000 copies/ML.
• have HIV-2 infection.
• have serious complications in organs including renal, circulatory, respiratory, digestive, endocrine, neural and immunological diseases and tumors.
• received treatment of hormones or other immunosuppressive drugs for a long time.
• with serious AIDS related or unrelated events.
• received immunosuppressive drugs or systemic cytotoxic drugs for more than 3 months before recruiting
• have poor compliance during treatment.
• drug addiction within 6 months, or the urine drug test is positive
• participate in other clinical trials currently
• pregnant, breastfeeding, or have fertility requirements.
• unable or unwilling to provide informed consents, or unable to comply with research requirements.
• Other serious situations that may hinder clinical trials.

Where it is running

• Beijing 302 Hospital — Beijing, China (enrolling)
• Beijing YouAn Hospital — Beijing, China (enrolling)
• Shenzhen Third People's Hospital — Shenzhen, China (enrolling)
• The Fifth Hospital of Shijiazhuang — Shijiazhuang, China (enrolling)

Full record on ClinicalTrials.gov

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