Leflunomide for Idiopathic Pulmonary Hemosiderosis in Children
Recruiting now · Phase 1/Phase 2
Conditions studied: Idiopathic Pulmonary Hemosiderosis, Leflunomide
In brief
The goal of this clinical trial is to compare Leflunomide in Idiopathic pulmonary hemosiderosis. The main questions it aims to answer are: * The efficacy and safety of Leflunomide in Idiopathic pulmonary hemosiderosis * The mechanism of leflunomide in treating Idiopathic pulmonary hemosiderosis Participants will be treated with leflunomide plus stroid. A comparison group: Researchers will compare the control group treated with stroid to see if the efficacy of Leflunomide would be better than control group.
Key facts
- Study ID
- NCT05937191
- Run by
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
- People needed
- 34
- Starts
- 2023-06-01
- Expected to finish
- 2026-12-31
- Last updated by the study team
- 2023-07-10
Who can join
Age: 0 and older, up to 18. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age range from 6 months to 18 years old;
- Diagnose as IPH;
- Parents or guardians agree to treatment and sign a written informed consent form.
You may not qualify if…
- Individuals who are allergic to any ingredients used in leflunomide tablets;
- Complicated with serious basic diseases (such as systemic malignant diseases, heart failure, liver and kidney failure, immune deficiency, serious infectious diseases, Lung transplantation or other patients with immediate surgical indications);
- Patients with other lung diseases;
- Have a history of abnormal coagulation or abnormal coagulation function in the past;
- Clinical trial participants who have previously participated in the treatment of flumiphene;
- Other situations where the researcher deems it inappropriate to participate in the study.
Where it is running
- Sun Yat-sen Memorial Hospital of Sun Yat-sen University — Guangzhou, Guangdong, China (enrolling)
Full record on ClinicalTrials.gov
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