Post-Brain Injury Walking and Balance Recovery Program

Stopped early · Not applicable

Conditions studied: Acquired Brain Injury, Stroke, Traumatic Brain Injury

In brief

The purpose of this study is to test the efficacy of a walking and balance training program designed to safely challenge and improve walking performance and balance in relation to walking speed, strength, endurance, and balance after traumatic brain injury (TBI). The aim and primary hypothesis of this research project is: Aim) Test and implement a new personalized intervention strategy, in addition to usual and customary care at an inpatient rehabilitation clinic, to improve patient outcomes with secondary conditions associated with impaired balance and walking that typically occur post brain injury. After validation of the locomotor Battery of tests, we will implement a personalized training strategy for individuals based on their battery profile. Hypothesis) Individuals training with this individualized protocol will demonstrate improved walking and balance outcomes and those with lesser pre-intervention impairment will improve at a greater rate than those with greater pre-intervention impairment.

Key facts

Study ID

NCT05934773

Run by

The University of Texas Medical Branch, Galveston

People needed

5

Starts

2022-08-18

Expected to finish

2025-04-04

Last updated by the study team

2025-12-24

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults ages 18 years and older
• All demographic groups will be invited to participate and would have equal access
• Post-TBI individuals currently enrolled at the Moody Neurorehabilitation Institute
• Ambulatory with or without assistive devices
• Subjects with expressive aphasia in the case of a caregiver able to provide assistance when needed
• English-speaking or have a certified interpreter that is English-speaking who will be present for interpretation during the study
• Medically stable (controlled hypertension, no arrhythmia, stable cardiovascular status)
• Able to provide written informed consent

You may not qualify if…

• Subjects with loss of lower limb
• History of serious cardiac disease (e.g., myocardial infarction)
• Uncontrolled blood pressure (systolic pressure >140 mmHg, diastolic blood pressure >90 mmHg)
• Subjects with receptive aphasia
• Presence of cerebellar and brainstem deficits
• Severe cognitive disorder
• Uncontrolled respiratory or metabolic disorders
• Major or acute musculoskeletal problems
• Spasticity management that included phenol block injections within 12 months or botulinum toxin injections within 4 months of the study
• Body weight greater than 250 pounds (due to robotic device weight restrictions)

Where it is running

• Moody Neurorehabilitation Institute — Galveston, Texas, United States

Full record on ClinicalTrials.gov

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