The Effects of Low Viscosity Chloroprocaine Ophthalmic Gel 3% on the Bactericidal Action of Povidone-Iodine

Completed · Phase 4

Conditions studied: Antiseptic, Anesthesia, Local

In brief

To evaluate if Iheezo's (chloroprocaine 3%) gel vehicle acts as a barrier on the ocular surface, potentially blocking the bactericidal action of povidone-iodine.

Key facts

Study ID: NCT05934253
Run by: Harrow Inc
People needed: 100
Starts: 2023-07-15
Expected to finish: 2024-02-15
Last updated by the study team: 2025-09-16

Who can join

Age: 18 and older, up to 99. Sex: any. Healthy volunteers: accepted.

You may qualify if…

Patients over age 18.
Able to comprehend and sign a statement of informed consent.

You may not qualify if…

Ocular surgery (e.g., intraocular, oculoplastic, corneal, or refractive surgical procedure) performed within the last 3 months or at any time that in the investigator's clinical judgment if it would interfere with the outcome measures of this study.
Clinically significant ocular trauma.
Diagnosis of lagophthalmos, or other severe eyelid abnormalities (entropion, ectropion, tumor, edema, blepharospasm, severe trichiasis, severe ptosis.)
Active ocular inflammation (uveitis, iritis, scleritis, episcleritis, keratitis, conjunctivitis) at the discretion of the investigator.
Active ocular infection (e.g., viral, bacterial, mycobacterial, protozoan or fungal infection or the cornea, conjunctiva, lacrimal gland, lacrimal sac or eyelids including hordeolum/stye).
Ocular infection within the last 3 months.
Moderate to severe (Grade 2-4) allergic, vernal or giant papillary conjunctivitis.
Patients who are under age 18, pregnant or breastfeeding, or who may become pregnant during participation in the study.
Monocular patients.

Where it is running

Brandon Eye Associates — Brandon, Florida, United States

Full record on ClinicalTrials.gov

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