Effect of Different E-cigarette Cooling Flavors on Adults' Sensory Experience TCORS 3.0

Completed · Not applicable

Conditions studied: E-Cig Use

In brief

This pilot sensory experiment will examine cooling from comparable concentrations of WS-3 and menthol to determine appropriate concentrations to use in the main study.

Key facts

Study ID

NCT05932693

Run by

Yale University

People needed

31

Starts

2024-09-03

Expected to finish

2025-01-09

Last updated by the study team

2026-02-18

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• 18 years or older
• Able to read and write
• Used e-cigarettes containing nicotine
• Use e-cigs in past 30 days
• No strong dislike of the menthol flavor
• Urine cotinine ≥200ng/ml
• Willing to abstain from tobacco/nicotine use 2 hrs prior to sessions

You may not qualify if…

• Known hypersensitivity to propylene glycol
• Pregnant or lactating females
• Uncontrolled asthma
• Nut/e-liquid flavorant allergy
• Current marijuana (tetrahydrocannabinol) vaping + E-cigarette or vaping use Associated Lung Injury (EVALI) symptoms
• Dislike of menthol flavor

Where it is running

• Yale School of Medicine — New Haven, Connecticut, United States

Full record on ClinicalTrials.gov

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