Impulsivity Domains and Subjective Response
Recruiting now · Early Phase 1 · Has a placebo group
Conditions studied: Alcohol Use Disorder
In brief
Findings from this project will determine the relationship between two vulnerability factors for Alcohol Use Disorder (AUD) in young adults: impulsivity and subjective response to alcohol. The results will identify badly needed, novel targets for prevention and treatment efforts to simultaneously reduce impulsivity and subjective responses in at-risk young adults.
Key facts
- Study ID
- NCT05929677
- Run by
- Jessica Weafer
- People needed
- 250
- Starts
- 2024-04-01
- Expected to finish
- 2027-09-01
- Last updated by the study team
- 2026-05-22
Who can join
Age: 21 and older, up to 25. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- 21-25 years old
- Report drinking to an estimated BAC > .08% at least once in the past 30 days based on responses on the Timeline Followback (TLFB)
- Report drinking at least twice weekly in the past 30 days based on responses on the TLFB
- Fluency in English
You may not qualify if…
- Any serious medical problems (e.g., liver disease, cardiac abnormality, pancreatitis, diabetes, neurological problems, and gastrointestinal disorders)
- Body weight < 110 or > 210 pounds
- Axis I psychiatric disorders including substance use disorder other than mild or moderate alcohol or mild cannabis use disorder
- Current alcohol withdrawal or history of medically-assisted detoxification
- Two positive breath alcohol concentration (BrAC) readings (i.e., > 0.00%) at an in-person screening appointment or experimental session
- Positive urine screen for illegal drugs other than cannabis
- Currently seeking or past-12-month history of inpatient or intensive treatment for addictive behaviors
- Current psychotropic medication use or receipt of a prescription for these medications in the past 30 days
- Psychosis or other psychiatric disability
- Pregnancy, nursing or lack of reliable birth control use for women
- Report smoking > 5 cigarettes per day (to avoid acute nicotine effects or withdrawal during experimental sessions)
Where it is running
- Northeastern University — Boston, Massachusetts, United States (enrolling)
- Ohio State University — Columbus, Ohio, United States (enrolling)
Full record on ClinicalTrials.gov
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